Peptide-HLA class I supertype binding prediction





The HLA binder peptide is defined based on predcition results conducted by NetMHC 4.0, where the peptide has been classified as a weak binder (the predicted Rank of Binding Level between 0.5% to 2%) or strong binder (the predicted Rank of Binding Level is equal to or lower than 0.5%).




75.5%24.5%
Non-binderBinderBinder vs. non-binder peptides
01000200030007654321
Number of HLA supertypes binding the peptidesNumber of peptidesNumber of HLA supertypes
#Peptides binding to 1 HLA supertype: 3351;

#Peptides binding to 2 HLA supertype: 907;

#Peptides binding to 3 HLA supertype: 218;

#Peptides binding to 4 HLA supertype: 68;

#Peptides binding to 5 HLA supertype: 11;

#Peptides binding to 6 HLA supertype: 7;

#Peptides binding to 7 HLA supertype: 2;

02004006008001000HLA-B5801HLA-B4001HLA-B3901HLA-B2705HLA-B1501HLA-B0801HLA-B0702HLA-A2601HLA-A2402HLA-A0301HLA-A0201HLA-A0101
Strong binderWeak binderNumbers of Strong and weak binders to different HLA supertypesNumber of peptidesHLA class I supertypes
HLA-A0101: WBs - 729
; SBs - 307
;
HLA-A0201: WBs - 339
; SBs - 109
;
HLA-A0301: WBs - 597
; SBs - 199
;
HLA-A2402: WBs - 498
; SBs - 149
;
HLA-A2601: WBs - 497
; SBs - 190
;
HLA-B0702: WBs - 238
; SBs - 48
;
HLA-B0801: WBs - 251
; SBs - 111
;
HLA-B1501: WBs - 327
; SBs - 124
;
HLA-B2705: WBs - 153
; SBs - 43
;
HLA-B3901: WBs - 323
; SBs - 78
;
HLA-B4001: WBs - 361
; SBs - 83
;
HLA-B5801: WBs - 353
; SBs - 93
;


73.6%26.4%
Non-binderBinderBinder vs. non-binder peptides
01000200030004000654321
Number of HLA supertypes binding the peptidesNumber of peptidesNumber of HLA supertypes
#Peptides binding to 1 HLA supertype: 4049;

#Peptides binding to 2 HLA supertype: 1129;

#Peptides binding to 3 HLA supertype: 267;

#Peptides binding to 4 HLA supertype: 87;

#Peptides binding to 5 HLA supertype: 6;

#Peptides binding to 6 HLA supertype: 6;

05001000HLA-B5801HLA-B4001HLA-B3901HLA-B2705HLA-B1501HLA-B0801HLA-B0702HLA-A2601HLA-A2402HLA-A0301HLA-A0201HLA-A0101
Strong binderWeak binderNumbers of Strong and weak binders to different HLA supertypesNumber of peptidesHLA class I supertypes
HLA-A0101: WBs - 896
; SBs - 386
;
HLA-A0201: WBs - 384
; SBs - 92
;
HLA-A0301: WBs - 743
; SBs - 262
;
HLA-A2402: WBs - 651
; SBs - 175
;
HLA-A2601: WBs - 628
; SBs - 208
;
HLA-B0702: WBs - 292
; SBs - 60
;
HLA-B0801: WBs - 352
; SBs - 159
;
HLA-B1501: WBs - 387
; SBs - 136
;
HLA-B2705: WBs - 227
; SBs - 69
;
HLA-B3901: WBs - 353
; SBs - 75
;
HLA-B4001: WBs - 438
; SBs - 85
;
HLA-B5801: WBs - 364
; SBs - 100
;


59.7%40.3%
BinderNon-binderBinder vs. non-binder peptides
01020321
Number of HLA supertypes binding the peptidesNumber of peptidesNumber of HLA supertypes
#Peptides binding to 1 HLA supertype: 26;

#Peptides binding to 2 HLA supertype: 10;

#Peptides binding to 3 HLA supertype: 1;

0510HLA-B5801HLA-B4001HLA-B3901HLA-B2705HLA-B1501HLA-B0801HLA-B0702HLA-A2601HLA-A2402HLA-A0301HLA-A0201HLA-A0101
Strong binderWeak binderNumbers of Strong and weak binders to different HLA supertypesNumber of peptidesHLA class I supertypes
HLA-A0101: WBs - 6
; SBs - 7
;
HLA-A0201: WBs - 9
; SBs - 2
;
HLA-A0301: WBs - 2
; SBs - 1
;
HLA-A2402: WBs - 2
; SBs - 1
;
HLA-A2601: WBs - 3
; SBs - 1
;
HLA-B0702: WBs - 2
; SBs - 1
;
HLA-B0801: WBs - 1
; SBs - 2
;
HLA-B1501: WBs - 0
; SBs - 1
;
HLA-B2705: WBs - 0
; SBs - 0
;
HLA-B3901: WBs - 5
; SBs - 0
;
HLA-B4001: WBs - 0
; SBs - 0
;
HLA-B5801: WBs - 1
; SBs - 2
;




050010004321
HLA binders - 8merNumber of peptidesNumber of HLA supertypes
01000200030007654321
HLA binders - 9merNumber of peptidesNumber of HLA supertypes
0100020003000654321
HLA binders - 10merNumber of peptidesNumber of HLA supertypes
05001000150020004321
HLA binders - 11merNumber of peptidesNumber of HLA supertypes
01000200054321
HLA binders - 12merNumber of peptidesNumber of HLA supertypes
010002000300054321
HLA binders - 13merNumber of peptidesNumber of HLA supertypes
010002000300040007654321
HLA binders - 14merNumber of peptidesNumber of HLA supertypes