Peptide-HLA class I supertype binding prediction



Fast peptide nevigation according to numbers of predicted binders to HLA supertype representatives:

The HLA binder peptide is defined based on predcition results conducted by NetMHC 4.0, where the peptide has been classified as a weak binder (the predicted Rank of Binding Level between 0.5% to 2%) or strong binder (the predicted Rank of Binding Level is equal to or lower than 0.5%).


    Virus: SARS-CoV-2


        Experiment: SARS-CoV-2_synthetic; EXP_001
75.5%24.5%
Non-binderBinderBinder vs. non-binder peptides
01000200030007654321
Number of HLA supertypes binding the peptidesNumber of peptidesNumber of HLA supertypes
 #Peptides binding to 1 HLA supertype: 3351;

#Peptides binding to 2 HLA supertype: 907;

#Peptides binding to 3 HLA supertype: 218;

#Peptides binding to 4 HLA supertype: 68;

#Peptides binding to 5 HLA supertype: 11;

#Peptides binding to 6 HLA supertype: 7;

#Peptides binding to 7 HLA supertype: 2;

02004006008001000HLA-B5801HLA-B4001HLA-B3901HLA-B2705HLA-B1501HLA-B0801HLA-B0702HLA-A2601HLA-A2402HLA-A0301HLA-A0201HLA-A0101
Strong binderWeak binderNumbers of Strong and weak binders to different HLA supertypesNumber of peptidesHLA class I supertypes
 HLA-A0101: WBs - 729
; SBs - 307
;
HLA-A0201: WBs - 339
; SBs - 109
;
HLA-A0301: WBs - 597
; SBs - 199
;
HLA-A2402: WBs - 498
; SBs - 149
;
HLA-A2601: WBs - 497
; SBs - 190
;
HLA-B0702: WBs - 238
; SBs - 48
;
HLA-B0801: WBs - 251
; SBs - 111
;
HLA-B1501: WBs - 327
; SBs - 124
;
HLA-B2705: WBs - 153
; SBs - 43
;
HLA-B3901: WBs - 323
; SBs - 78
;
HLA-B4001: WBs - 361
; SBs - 83
;
HLA-B5801: WBs - 353
; SBs - 93
;


        Experiment: SARS-CoV-2_FUSION; EXP_002
73.6%26.4%
Non-binderBinderBinder vs. non-binder peptides
01000200030004000654321
Number of HLA supertypes binding the peptidesNumber of peptidesNumber of HLA supertypes
 #Peptides binding to 1 HLA supertype: 4049;

#Peptides binding to 2 HLA supertype: 1129;

#Peptides binding to 3 HLA supertype: 267;

#Peptides binding to 4 HLA supertype: 87;

#Peptides binding to 5 HLA supertype: 6;

#Peptides binding to 6 HLA supertype: 6;

05001000HLA-B5801HLA-B4001HLA-B3901HLA-B2705HLA-B1501HLA-B0801HLA-B0702HLA-A2601HLA-A2402HLA-A0301HLA-A0201HLA-A0101
Strong binderWeak binderNumbers of Strong and weak binders to different HLA supertypesNumber of peptidesHLA class I supertypes
 HLA-A0101: WBs - 896
; SBs - 386
;
HLA-A0201: WBs - 384
; SBs - 92
;
HLA-A0301: WBs - 743
; SBs - 262
;
HLA-A2402: WBs - 651
; SBs - 175
;
HLA-A2601: WBs - 628
; SBs - 208
;
HLA-B0702: WBs - 292
; SBs - 60
;
HLA-B0801: WBs - 352
; SBs - 159
;
HLA-B1501: WBs - 387
; SBs - 136
;
HLA-B2705: WBs - 227
; SBs - 69
;
HLA-B3901: WBs - 353
; SBs - 75
;
HLA-B4001: WBs - 438
; SBs - 85
;
HLA-B5801: WBs - 364
; SBs - 100
;


        Experiment: SARS-CoV-2; EXP_003
59.7%40.3%
BinderNon-binderBinder vs. non-binder peptides
01020321
Number of HLA supertypes binding the peptidesNumber of peptidesNumber of HLA supertypes
 #Peptides binding to 1 HLA supertype: 26;

#Peptides binding to 2 HLA supertype: 10;

#Peptides binding to 3 HLA supertype: 1;

0510HLA-B5801HLA-B4001HLA-B3901HLA-B2705HLA-B1501HLA-B0801HLA-B0702HLA-A2601HLA-A2402HLA-A0301HLA-A0201HLA-A0101
Strong binderWeak binderNumbers of Strong and weak binders to different HLA supertypesNumber of peptidesHLA class I supertypes
 HLA-A0101: WBs - 6
; SBs - 7
;
HLA-A0201: WBs - 9
; SBs - 2
;
HLA-A0301: WBs - 2
; SBs - 1
;
HLA-A2402: WBs - 2
; SBs - 1
;
HLA-A2601: WBs - 3
; SBs - 1
;
HLA-B0702: WBs - 2
; SBs - 1
;
HLA-B0801: WBs - 1
; SBs - 2
;
HLA-B1501: WBs - 0
; SBs - 1
;
HLA-B2705: WBs - 0
; SBs - 0
;
HLA-B3901: WBs - 5
; SBs - 0
;
HLA-B4001: WBs - 0
; SBs - 0
;
HLA-B5801: WBs - 1
; SBs - 2
;


        Proteome-wide HLA binding prediction of using the proteome data of Human SARS coronavirus and Severe acute respiratory syndrome coronavirus 2


        The predicted binding peptides are derived from the combination of the protein seqeunce data of Human SARS coronavirus and Severe acute respiratory syndrome coronavirus 2. Download the whole proteome HLA binding predictions here.
050010004321
HLA binders - 8merNumber of peptidesNumber of HLA supertypes
01000200030007654321
HLA binders - 9merNumber of peptidesNumber of HLA supertypes
0100020003000654321
HLA binders - 10merNumber of peptidesNumber of HLA supertypes
05001000150020004321
HLA binders - 11merNumber of peptidesNumber of HLA supertypes
01000200054321
HLA binders - 12merNumber of peptidesNumber of HLA supertypes
010002000300054321
HLA binders - 13merNumber of peptidesNumber of HLA supertypes
010002000300040007654321
HLA binders - 14merNumber of peptidesNumber of HLA supertypes